2 COMPLETELY AVOIDABLE DISEASES OF CHILDHOOD

january 24th, 2022

Redo
Non Alcoholic Fatty Liver Disease, NAFLD

Non Alcoholic Steatohepatitis, NASH

When I was in medical school in the early 90's, the primary cause of fatty liver disease in adults was alcohol abuse. Over the last 20 years, the obesity epidemic and associated fatty liver disease, NAFLD, has taken over first place. Unfortunately, this is no longer an adult only phenomena. Akin to type II diabetes mellitus, children are now suffering increasing rates of NASH and then NAFLD.

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Fructose redo

 Januray 24th, 2022

 In preparation for the upcoming podcast with Dr. Rick Johnson. We are going to discuss the survival switch and fructose metabolism in specific. It will be another life changing discussion for many of us.


We all are paying more attention to the effects of lifestyle choices on our health especially as it relates to Covid 19. One of the primary lifestyle choices that is hurting us is the over consumption of refined carbohydrates or sugars, in particular the molecule fructose.

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COVID Pathophysiology 2021/2022

 January 17th, 2022

 

The massive update to this theory is finished for now: it is long, complex and interesting!

SARS2, the virus that causes Covid – 19, is now known to be an infectious disease with features of a human disease that span the spectrum from asymptomatic to profoundly dysregulated immune system responses leading to both aggressive inflammation and autoimmunity in the moderately to severely affected persons. It is now very clear that the vast majority of these significantly affected

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Vaccine Effectiveness Goes Down The Drain

January 17th, 2022

By Viany Prasad

"Some argue there is still a justification to boost because you can help prevent hospitals from being overwhelmed. Sadly, that argument fails in several ways. First, you have no evidence boosting younger people will slow hospitalizations. A vaccinated younger person already has very low risk of being hospitalized. Boosting may not further lower what is already very low. We simply have no evidence. Event rates are sparse at those ages.

Second, this argument would mean the state could tell people what to eat and how much to exercise, and how much to drink.

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Omicron Overview - The world of omicron as I see it now

January 17th, 2022

Ugh - 2 weeks changes everything

My partner, Dr. Koontz stated the other day, that nature is vaccinating the US with Omicron since we couldn't do it. He was present during measles outbreaks in Dallas, Texas during his training and he noted this feels closer to that than anything in his career. He is correct. Everyone will see this virus sooner or later this year. Hopefully, since we cannot vaccinate this virus into submission like measles, this will become like seasonal influenza where we have some a priori immunity leading to less death. Fingers crossed.

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Volume 12, Letter 5 Coronavirus Update 53

January 17th, 2022

How things change dramatically in 2 weeks again!

All vaccines are no longer working well to prevent transmission of SARS2 variant Omicron. The good news remains that the vaccines prevent bad outcomes which should be the message to all. Please get vaccinated if you have no prior Covid immunity and/or have natural disease but also have major risk factors. Omicron is 91% less risky then Delta. However, 9% comparative residual risk in over a 100 million unvaccinated is still a large number of seriously sick people.

North Carolina is in a huge wave now as with the rest of the country. I have not seen or heard of any hospitals being overwhelmed here but that is happening in many parts of the country now. North Carolina has between 60 and 90% of Covid beds filled according to the hospital reports.

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Forgiveness

January 10th, 2022

Redo: Forgiveness is an unfortunately underutilized cure for heartache and pain. We all at some point in life will suffer from an intentional or unintentional wrong that leaves us wounded, angry and potentially vengeful. This triad of dangerous feelings will usually worsen our sense of self if we act upon them or hold them close. How many movies have we seen or books read that show the lead character suffering from anger held too tightly?

An acute or, worse yet, chronic unremitting sense of anger and wounding will engage our sympathetic nervous system's fight or flight mode to protect us from further harm. In an effort to save ourselves, we are likely to run away from the stressor or attempt to compartmentalize it, aka wall it off. How often does this work? Rarely!

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Back in a Covid Time Capsule

 

January 10th, 2022

 April 2020 - "Flattening the curve has occurred effectively in most parts of the United States. That is a good thing because we still have serious supply chain issues with protective gear for healthcare workers. I have friends that work for companies that produce the PPE materials and the stories that I am hearing as to the why are frustrating and a clear sign that the supply chain needs to be United States based form here on out. That being said, where do we go from here? We have discussed this on and off over the last few weeks.

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Letting Go

January 10th, 2022

When I think of the words letting go, I conjure up thoughts of past losses. Whether it is a cat or dog that passed away, friends from a stage of life, past hurts, lost human loved ones, failed endeavors and so much more, we all have loss and have or should have let go of the pain and suffering that holds back our growth. Letting go can also be as simple as relinquishing the desire for today's plans when something unexpected requires your attention. It can also be very complicated as in releasing the hurt of a trauma or loss. However, letting go is just that, letting it go. So let it go and be free.

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Section III - The White Board

January 3rd, 2022

I am in the process of doing a massive update to this theory:

For the Unifying Theory of SARS2/COVID19 pathology that was published in September, please follow this link. In this piece, I lay out what appears to be the pathway to infection and subsequent significant illness. It will be updated in the coming months.

 

Dr. M

We Can't Just Impose Restrictions Whenever COVID-19 Surges. Here's a Better Plan for 2022

January 3rd, 2022

 BY MONICA GANDHI AND JEANNE NOBLE

"The arrival of Omicron, the latest and most transmissible COVID-19 variant to date, underscores the tremendous need for updated COVID-19 policy in the U.S. We always knew it would be difficult to contain a highly transmissible respiratory virus before Omicron. The arrival of the Delta variant forced us to abandon our goal of “herd immunity.” With the arrival of Omicron, a more appropriate goal of protecting those at risk of severe breakthrough infections is now in order. A new framework in light of Omicron will help move us beyond the continuous cycle of removing and reinstating COVID restrictions based on metrics that

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Coronavirus Update 52

 

 January 3rd 2022

Omicron Overview - The world of omicron as I see it now

OMICRON IS A MORE INFECTIOUS BUT LESS SEVERE VARIANT ACCORDING TO ALL REPORTS - Amen

1) Omicron is everywhere in the US now, as expected.
2) Hospitalizations and deaths remain decoupled from cases meaning that we are on our way to mild COVID endemicity and likely the end of the pandemic as we know it based on Delta and Alpha's severity

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Volume 12, Letter 3

January 3rd, 2022 

Omicron is highly transmissible and cruising throughout the country especially in the colder states. We are at the highest daily case rate since the pandemic started. This week - 486,000 + cases in a single day. The case number is actually much higher due to uncounted positive at home tests. However, the blessing is that death and hospitalization rates are not following at all. Therefore, we need to keep our focus on hospitalization and not case number.

North Carolina has begun a big wave as with the rest of the country. South Africa has already turned the corner after a 6 week run. This may bode well for this wave as well.

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Preventing Food Allergies

 

December 27th, 2021

Without getting into the science this time, lets just look at the to do:

1) Mothers should eat a very healthy whole foods diet while pregnant to encourage the best quality gut flora to pass to her babe. Focus on high volumes of fiber and gut microbe promoting plants

2) Deliver vaginally if possible

3) Breastfeed if possible

4) Consider adding Bifidobacter infantis via Evivo probiotic to enhance HMO metabolism and immune gut tolerance

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Exercise alters cancer risk

December 27th, 2021

"Exercise causes muscles to secrete proteins called myokines into our blood – and researchers from ECU’s Exercise Medicine Research Institute have learned these myokines can suppress tumour growth and even help actively fight cancerous cells.

A clinical trial saw obese prostate cancer patients undergo regular exercise training for 12 weeks, giving blood samples before and after the exercise program. Researchers then took the samples and applied them directly onto living prostate cancer cells." (Cifarelli et. al. 2021)

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Lymphatics

December 27th, 2021

Lymphatics - a plumbing system that follows the circulatory system throughout the body including the brain where it is called the glymphatics. The function of these passively moving tubes is to transport fats around the body, clear cellular debris returning it to the liver and spleen, move fluid in and out of tissue to maintain fluid balance, transport and help immune cells function. These are critical functions of metabolism, immunity and detoxification that when disrupted lead to chronic diseases of aging including edema, hypertension, autoimmunity and cardiovascular disease.

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SECTION II Omicron

December 20th, 2021

The Atlantic often has very good articles to learn from, but they also tend to push an agenda that doesn't make complete sense based on the data that is emerging. In a piece by Rachel Gutman, we see the beginnings of another fear based hypothetical reality to drive more booster vaccinations in those who were previously infected and vaccinated or just vaccinated. The article goes off the rails to discuss incredible hospital overwhelm scenarios in the United States that is at the highest vaccination status of the whole pandemic. The data is not supporting any of these hospital contentions of overwhelm or severity based on all emerging reports. The only major risk for a bad outcome remains co morbid disease, age and unvaccinated naive status.

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  Omicron Overview - The world of omicron as I see it

December 20th, 2021

1) It appears that omicron is everywhere in the US now, as expected.
2) Hospitalizations and deaths remain decoupled from cases meaning that we are on our way to mild COVID endemicity.
3) Your risk of death if you have had covid naturally or been vaccinated appears now to be very very very low with Omicron or Delta.
4) The caveat to number three is that if you are older with co-morbid disease in a significant stage, your risk of death is much higher. But, this is true for influenza and other severe viral illnesses as well at this point because of the inflammation that pervades the body from these diseases over time.

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Volume 12, Letter 1 Coronavirus Update 51

December 20th, 2021

The beginning of year 12 starts with Covid. Go figure!
Omicron appears less deadly and more contagious.

Early reports are showing vast increases in spread rate but also significant reductions in lung based inflammation and disease. If these early reports play out to be true, we are in for a nice denoument to this pandemic. Fingers crossed.

North Carolina remains in relative normalcy in most places. The northern United States and especially the cities that are entering winter like conditions are seeing significant increases. Europe is also seeing large spikes in the colder climate countries.

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My Conclusion

December 13th, 2021

After 11 years of work, reading and learning for the SPA newsletter, I have come to a broad conclusion: We are in constant flux with health. The variables to health are vast and changing real time.

This puts us in a state of constant vigilance for change needs in order to adapt to our environment. I have thoroughly enjoyed the process of gathering and presenting this data and information to you in a useable and understandable form.

Covid has been an extreme example of this process. I would have never dreamed that I would write 50+ newsletters on one topic. Amazing.

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